Gave a talk last night with Norm Santos about full-stack web application testing using Node.js, Zombie.js and Vows. We presented it to TriangleJS meetup. It was pretty well-received.
My team's usage of Zombie/Vows has petered off a little as we've moved into other projects, but it's definitely a concept I'd like to revisit when we get a little time. As our app solidifies more, we're going to need more of this type of testing, in addition to our typical unit- and functional-testing.